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PHARMACY INDIA on Instagram: "💊 Methotrexate – Mode of Action ➡️ Methotrexate inhibits the enzyme dihydrofolate reductase (DHFR), which is essential for the synthesis of DNA, RNA, and proteins. ➡️ This leads to decreased cell proliferation, especially in rapidly dividing cells like cancer cells and activated immune cells. ➡️ Hence, it’s used as an antineoplastic and immunosuppressant drug in conditions like cancer, rheumatoid arthritis, and psoriasis. 📘 Key Point: Methotrexate = Folate antagon
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