Leptomeningeal disease (also known as LMD, leptomeningeal metastases, or LM) is cancer in your cerebrospinal fluid and in your leptomeninges, the membranes that surround your brain and spinal cord.

Leptomeningeal disease (LMD), or spread of cancer cells into the pia and arachnoid membranes encasing the brain and spinal cord, is associated with high symptom burden and poor survival at 2 to …

Leptomeningeal disease (LMD), also known as leptomeningeal carcinomatosis, is a condition where cancer spreads to the brain, spinal fluid and leptomeninges, the thin layers of tissue around the brain …

Jul 14, 2025 · Leptomeningeal disease (LMD; also referred to as leptomeningeal metastases or carcinomatous meningitis) is a rare but frequently devastating complication of advanced cancer from …

Leptomeningeal metastasis—also called leptomeningeal carcinomatosis, leptomeningeal disease, or simply “LMD”—is the spread of cancer to a particular part of the brain called the leptomeninges.

Leptomeningeal Disease (LMD) happens when cancer cells invade the fluid and protective membranes surround the brain and spinal cord. Learn more from UPMC.

Apr 1, 2025 · Leptomeningeal disease (LMD) is a devastating complication of metastatic cancer, characterized by the spread of malignant cells to the cerebrospinal fluid (CSF) and the leptomeninges.

Leptomeningeal disease (LMD) occurs when cancer cells spread to the leptomeninges—the two inner layers of tissue that cover the brain and spinal cord (the arachnoid mater and pia mater).

Leptomeningeal disease (LMD) occurs when cancer cells migrate from the breast, lung, or other parts of the body to the cerebrospinal fluid (CSF) or meninges. CSF is the liquid that circulates nutrients and …

Sep 30, 2025 · Leptomeningeal metastatic disease (LMD) is associated with poor prognosis and imposes severe symptomatic limitations on functional status and quality of life.