For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

Scientists at St. Jude Children's Research Hospital and Washington University School of Medicine have discovered why the flu vaccine can perform poorly. They found that a specific type of immune cell, ...

For the immune system to effectively combat pathogens, antibody responses must be precisely controlled. So-called follicular ...

Scientists have uncovered how a key type of immune cell adapts its behavior depending on the type of infection, paving the way for better vaccines and advancing research into immune-related diseases.

Traditionally, in single-variant experiments, cells are engineered to express a single MHC-II allele so that every recovered peptide can be assigned unambiguously, but only a few alleles are covered.

You have full access to this article via your institution. This study strongly suggests that tissue-dependent and context-dependent mechanisms drive T H 2 cell development in response to inhaled ...

HIV can damage the brain and cause memory and cognitive problems. And once HIV enters the brain, it does not leave. HIV targets a type of immune cell called helper T cells. These immune cells move ...

For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important type of human immune cell-known as helper T cells-from stem cells in a ...

Immunotherapies – treatments that aim to make the body's natural immune system more effective – are becoming more widely used ...

Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi were awarded the 2025 Nobel Prize in Physiology or Medicine on Monday for their collective work in the discovery of specialized immune cells that roam ...

Scientists have uncovered how CD4+ T cells can target cancer cells that evade CD8+ T cells, challenging long-held views and ...

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers headed by a team at The Ohio State University College of Medicine have shown how ...