AMSBIO (Oxford, UK) has launched a new range of deubiquitinating (DUB) enzyme assay kits supplied in a convenient and easy-to-use 96-well assay format. With minimal setup required and no need for ...
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Mastering enzyme assays for better research results
Enzyme assays are essential tools for understanding how enzymes function, from drug discovery to food science. Careful control of assay conditions, awareness of kinetic complexities, and adoption of ...
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Biochemical assays are a common approach used to identify inhibitors of epigenetic-modifying enzymes. Challenges that arise when designing these assays are centered on choosing histone substrates that ...
Persistent bottlenecks in biocatalyst development can be alleviated through fully automated enzyme analysis. Enzymes—the biological catalysts that accelerate chemical reactions inside cells—play ...
A new type of assay based on click chemistry will make it possible to carry out high-throughput screens to find inhibitors of the gut hormone ghrelin, a target for obesity and diabetes medications.
The selectivity of an enzyme inhibitor is a key determinant of its usefulness as a tool compound or its safety as a drug. Yet selectivity is never assessed comprehensively in the early stages of the ...
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