Epithelial ovarian cancer (EOC) is an aggressive malignancy with limited therapeutic options. Poly(ADP-ribose) polymerase inhibitors (PARPi) have shown remarkable efficacy, especially in BRCA-mutant ...
Recent Perha Pharmaceuticals patents describe imidazolone derivatives acting as inhibitors of dual specificity protein kinase CLK1 and/or CLK4 and/or and dual-specificity ...
Researchers from Chengdu Zeling Biomedical Technology Co. Ltd. presented the discovery and preclinical evaluation of novel CDC2-like kinase 1 (CLK1) inhibitors as autophagy inducers for the treatment ...
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